Family reunion via error correction: an efficient analysis of duplex sequencing data

BACKGROUND: Duplex sequencing is the most accurate approach for identification of sequence variants present at very low frequencies. Its power comes from pooling together multiple descendants of both strands of original DNA molecules, which allows distinguishing true nucleotide substitutions from PC...

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Detalles Bibliográficos
Autores principales: Stoler, Nicholas, Arbeithuber, Barbara, Povysil, Gundula, Heinzl, Monika, Salazar, Renato, Makova, Kateryna D, Tiemann-Boege, Irene, Nekrutenko, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057607/
https://www.ncbi.nlm.nih.gov/pubmed/32131723
http://dx.doi.org/10.1186/s12859-020-3419-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057607/
https://www.ncbi.nlm.nih.gov/pubmed/32131723
http://dx.doi.org/10.1186/s12859-020-3419-8

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