Increased Bone Marrow (18)F-Choline Uptake in a Patient with Hepatocellular Carcinoma and Thalassemia Intermedia

A 57-year-old male with history of thalassemia intermedia and hepatocellular carcinoma underwent a positron emission tomography/computed tomography (PET/CT) scan with (18)F-choline before radioembolization procedure with (90)Y-microspheres. The PET/CT scan with (18)F-choline demonstrated highly incr...

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Detalles Bibliográficos
Autor principal: Filippi, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2020
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057729/
https://www.ncbi.nlm.nih.gov/pubmed/32079389
http://dx.doi.org/10.4274/mirt.galenos.2019.03064
Descripción
Sumario:A 57-year-old male with history of thalassemia intermedia and hepatocellular carcinoma underwent a positron emission tomography/computed tomography (PET/CT) scan with (18)F-choline before radioembolization procedure with (90)Y-microspheres. The PET/CT scan with (18)F-choline demonstrated highly increased tracer incorporation within a gross lesion in the hepatic dome coupled with diffuse activity in bone marrow, this latter aspect was probably due to the compensatory hematopoiesis stimulation induced by chronic hemolysis. This pattern of skeletal (18)F-choline uptake should be considered as a peculiar PET/CT finding in thalassemic patients.

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