Increased Bone Marrow (18)F-Choline Uptake in a Patient with Hepatocellular Carcinoma and Thalassemia Intermedia

A 57-year-old male with history of thalassemia intermedia and hepatocellular carcinoma underwent a positron emission tomography/computed tomography (PET/CT) scan with (18)F-choline before radioembolization procedure with (90)Y-microspheres. The PET/CT scan with (18)F-choline demonstrated highly incr...

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Detalles Bibliográficos
Autor principal: Filippi, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2020
Materias:
Interesting Images
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057729/
https://www.ncbi.nlm.nih.gov/pubmed/32079389
http://dx.doi.org/10.4274/mirt.galenos.2019.03064
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author Filippi, Luca
author_facet Filippi, Luca
author_sort Filippi, Luca
collection PubMed
description A 57-year-old male with history of thalassemia intermedia and hepatocellular carcinoma underwent a positron emission tomography/computed tomography (PET/CT) scan with (18)F-choline before radioembolization procedure with (90)Y-microspheres. The PET/CT scan with (18)F-choline demonstrated highly increased tracer incorporation within a gross lesion in the hepatic dome coupled with diffuse activity in bone marrow, this latter aspect was probably due to the compensatory hematopoiesis stimulation induced by chronic hemolysis. This pattern of skeletal (18)F-choline uptake should be considered as a peculiar PET/CT finding in thalassemic patients.
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spelling pubmed-70577292020-03-16 Increased Bone Marrow (18)F-Choline Uptake in a Patient with Hepatocellular Carcinoma and Thalassemia Intermedia Filippi, Luca Mol Imaging Radionucl Ther Interesting Images A 57-year-old male with history of thalassemia intermedia and hepatocellular carcinoma underwent a positron emission tomography/computed tomography (PET/CT) scan with (18)F-choline before radioembolization procedure with (90)Y-microspheres. The PET/CT scan with (18)F-choline demonstrated highly increased tracer incorporation within a gross lesion in the hepatic dome coupled with diffuse activity in bone marrow, this latter aspect was probably due to the compensatory hematopoiesis stimulation induced by chronic hemolysis. This pattern of skeletal (18)F-choline uptake should be considered as a peculiar PET/CT finding in thalassemic patients. Galenos Publishing 2020-02 2020-02-17 /pmc/articles/PMC7057729/ /pubmed/32079389 http://dx.doi.org/10.4274/mirt.galenos.2019.03064 Text en ©Copyright 2020 by Turkish Society of Nuclear Medicine | Molecular Imaging and Radionuclide Therapy published by Galenos Yayınevi. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Interesting Images
Filippi, Luca
Increased Bone Marrow (18)F-Choline Uptake in a Patient with Hepatocellular Carcinoma and Thalassemia Intermedia
title Increased Bone Marrow (18)F-Choline Uptake in a Patient with Hepatocellular Carcinoma and Thalassemia Intermedia
title_full Increased Bone Marrow (18)F-Choline Uptake in a Patient with Hepatocellular Carcinoma and Thalassemia Intermedia
title_fullStr Increased Bone Marrow (18)F-Choline Uptake in a Patient with Hepatocellular Carcinoma and Thalassemia Intermedia
title_full_unstemmed Increased Bone Marrow (18)F-Choline Uptake in a Patient with Hepatocellular Carcinoma and Thalassemia Intermedia
title_short Increased Bone Marrow (18)F-Choline Uptake in a Patient with Hepatocellular Carcinoma and Thalassemia Intermedia
title_sort increased bone marrow (18)f-choline uptake in a patient with hepatocellular carcinoma and thalassemia intermedia
topic Interesting Images
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057729/
https://www.ncbi.nlm.nih.gov/pubmed/32079389
http://dx.doi.org/10.4274/mirt.galenos.2019.03064
work_keys_str_mv AT filippiluca increasedbonemarrow18fcholineuptakeinapatientwithhepatocellularcarcinomaandthalassemiaintermedia

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