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TNF-α-mediated epithelial-to-mesenchymal transition regulates expression of immune checkpoint molecules in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the fastest growing cause of cancer-related deaths globally. Epithelial-to-mesenchymal transition (EMT) is a cellular process that confers HCC tumor cells with the ability to evade the immune system. Immune escape in most tumors, including HCC, is controlled by immu...

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Detalles Bibliográficos
Autores principales: Shrestha, Ritu, Bridle, Kim R., Crawford, Darrell H.G., Jayachandran, Aparna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057769/
https://www.ncbi.nlm.nih.gov/pubmed/32319631
http://dx.doi.org/10.3892/mmr.2020.10991