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Sulforaphane suppresses carcinogenesis of colorectal cancer through the ERK/Nrf2-UDP glucuronosyltransferase 1A metabolic axis activation

The long pre-cancerous state of colorectal cancer (CRC) provides an opportunity to prevent the occurrence and development of CRC. The detoxification of CRC food-borne carcinogenic heterocyclic amines is highly dependent on UDP glucuronosyltransferase 1A (UGT1A)-mediated glucuronidation. Sulforaphane...

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Detalles Bibliográficos
Autores principales:	Hao, Qian, Wang, Min, Sun, Nuan-Xin, Zhu, Cheng, Lin, Ying-Min, Li, Cui, Liu, Fang, Zhu, Wen-Wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057772/ https://www.ncbi.nlm.nih.gov/pubmed/32323779 http://dx.doi.org/10.3892/or.2020.7495

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