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SHARPIN regulates cell proliferation of cutaneous basal cell carcinoma via inactivation of the transcriptional factors GLI2 and c-JUN

SHANK-associated RH domain-interacting protein (SHARPIN) is a component of the linear ubiquitin chain assembly complex that can enhance the NF-κB and JNK signaling pathways, acting as a tumor-associated protein in a variety of cancer types. The present study investigated the role of SHARPIN in cutan...

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Detalles Bibliográficos
Autores principales: Yang, Yao, Liang, Yan-Hua, Zheng, Yan, Tang, Ling-Jie, Zhou, Si-Tong, Zhu, Jing-Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057814/
https://www.ncbi.nlm.nih.gov/pubmed/32319607
http://dx.doi.org/10.3892/mmr.2020.10981