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RUNX1 Mutations in the Leukemic Progression of Severe Congenital Neutropenia
Somatic RUNX1 mutations are found in approximately 10% of patients with de novo acute myeloid leukemia (AML), but are more common in secondary forms of myelodysplastic syndrome (MDS) or AML. Particularly, this applies to MDS/AML developing from certain types of leukemia-prone inherited bone marrow f...
Autores principales: | Olofsen, Patricia A., Touw, Ivo P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Molecular and Cellular Biology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057833/ https://www.ncbi.nlm.nih.gov/pubmed/32041395 http://dx.doi.org/10.14348/molcells.2020.0010 |
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