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The Clinical, Molecular, and Mechanistic Basis of RUNX1 Mutations Identified in Hematological Malignancies

RUNX1 plays an important role in the regulation of normal hematopoiesis. RUNX1 mutations are frequently found and have been intensively studied in hematological malignancies. Germline mutations in RUNX1 cause familial platelet disorder with predisposition to acute myeloid leukemia (FPD/AML). Somatic...

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Detalles Bibliográficos
Autores principales:	Yokota, Asumi, Huo, Li, Lan, Fengli, Wu, Jianqiang, Huang, Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Molecular and Cellular Biology 2020
Materias:	Minireview
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057846/ https://www.ncbi.nlm.nih.gov/pubmed/31964134 http://dx.doi.org/10.14348/molcells.2019.0252

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