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Impaired B Cell Function in Mice Lacking Perforin-2

Perforin-2 (P2) is a pore-forming protein with cytotoxic activity against intracellular bacterial pathogens. P2 knockout (P2KO) mice are unable to control infections and die from normally non-lethal bacterial infections. Here we show that P2KO mice as compared to WT mice show significantly higher le...

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Detalles Bibliográficos
Autores principales:	Frasca, Daniela, Diaz, Alain, Romero, Maria, Vazquez, Thomas, Strbo, Natasa, Romero, Laura, McCormack, Ryan M., Podack, Eckhard R., Blomberg, Bonnie B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057857/ https://www.ncbi.nlm.nih.gov/pubmed/32180773 http://dx.doi.org/10.3389/fimmu.2020.00328

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