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MicroRNA-22 mediates the cisplatin resistance of osteosarcoma cells by inhibiting autophagy via the PI3K/Akt/mTOR pathway
Osteosarcoma (OS) is the most common primary malignant tumor of the bone affecting children and adolescents. Chemotherapy is now considered as a standard component of OS treatment, not only for children, but also for adults. However, chemoresistance continues to pose a challenge to therapy. Inhibiti...
Autores principales: | Meng, Chen-Yang, Zhao, Zhen-Qun, Bai, Rui, Zhao, Wei, Wang, Yu-Xing, Xue, Hui-Qin, Sun, Liang, Sun, Chao, Feng, Wei, Guo, Shi-Bing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057943/ https://www.ncbi.nlm.nih.gov/pubmed/32323781 http://dx.doi.org/10.3892/or.2020.7492 |
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