Cargando…
The Two-Species Model of transketolase explains donor substrate-binding, inhibition and heat-activation
We recently characterised a low-activity form of E. coli transketolase, TK(low), which also binds the cofactor thiamine pyrophosphate (TPP) with an affinity up to two-orders of magnitude lower than the previously known high TPP-affinity and high-activity form, TK(high), in the presence of Mg(2+). We...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057962/ https://www.ncbi.nlm.nih.gov/pubmed/32139871 http://dx.doi.org/10.1038/s41598-020-61175-z |