The evolution of zebrafish RAG2 protein is required for adapting to the elevated body temperature of the higher endothermic vertebrates

The recombination activating gene (RAG or RAG1/RAG2 complex)-mediated adaptive immune system is a hallmark of jawed vertebrates. It has been reported that RAG originated in invertebrates. However, whether RAG further evolved once it arose in jawed vertebrates remains largely unknown. Here, we found...

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Detalles Bibliográficos
Autores principales: Sun, Ao, Xu, Ke, Liu, Haifeng, Li, Hua, Shi, Yaohuang, Zhu, Xiaoyan, Liang, Tao, Li, Xinyue, Cao, Xianxia, Ji, Yanhong, Jiang, Taijiao, Xu, Chenqi, Liu, Xiaolong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057966/
https://www.ncbi.nlm.nih.gov/pubmed/32139788
http://dx.doi.org/10.1038/s41598-020-61019-w

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