Cargando…
Development of glass micro-electrodes for local electric field, electrical conductivity, and pH measurements
In micro- and nanofluidic devices, liquid flows are often influenced by ionic currents generated by electric fields in narrow channels, which is an electrokinetic phenomenon. Various technologies have been developed that are analogous to semiconductor devices, such as diodes and field effect transis...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058011/ https://www.ncbi.nlm.nih.gov/pubmed/32139704 http://dx.doi.org/10.1038/s41598-020-60713-z |
_version_ | 1783503782917701632 |
---|---|
author | Doi, Kentaro Asano, Naoki Kawano, Satoyuki |
author_facet | Doi, Kentaro Asano, Naoki Kawano, Satoyuki |
author_sort | Doi, Kentaro |
collection | PubMed |
description | In micro- and nanofluidic devices, liquid flows are often influenced by ionic currents generated by electric fields in narrow channels, which is an electrokinetic phenomenon. Various technologies have been developed that are analogous to semiconductor devices, such as diodes and field effect transistors. On the other hand, measurement techniques for local electric fields in such narrow channels have not yet been established. In the present study, electric fields in liquids are locally measured using glass micro-electrodes with 1-μm diameter tips, which are constructed by pulling a glass tube. By scanning a liquid poured into a channel by glass micro-electrodes, the potential difference in a liquid can be determined with a spatial resolution of the size of the glass tip. As a result, the electrical conductivity of sample solutions can be quantitatively evaluated. Furthermore, combining two glass capillaries filled with buffer solutions of different concentrations, an ionic diode that rectifies the proton conduction direction is constructed, and the possibility of pH measurement is also demonstrated. Under constant-current conditions, pH values ranging from 1.68 to 9.18 can be determined more quickly and stably than with conventional methods that depend on the proton selectivity of glass electrodes under equilibrium conditions. |
format | Online Article Text |
id | pubmed-7058011 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-70580112020-03-12 Development of glass micro-electrodes for local electric field, electrical conductivity, and pH measurements Doi, Kentaro Asano, Naoki Kawano, Satoyuki Sci Rep Article In micro- and nanofluidic devices, liquid flows are often influenced by ionic currents generated by electric fields in narrow channels, which is an electrokinetic phenomenon. Various technologies have been developed that are analogous to semiconductor devices, such as diodes and field effect transistors. On the other hand, measurement techniques for local electric fields in such narrow channels have not yet been established. In the present study, electric fields in liquids are locally measured using glass micro-electrodes with 1-μm diameter tips, which are constructed by pulling a glass tube. By scanning a liquid poured into a channel by glass micro-electrodes, the potential difference in a liquid can be determined with a spatial resolution of the size of the glass tip. As a result, the electrical conductivity of sample solutions can be quantitatively evaluated. Furthermore, combining two glass capillaries filled with buffer solutions of different concentrations, an ionic diode that rectifies the proton conduction direction is constructed, and the possibility of pH measurement is also demonstrated. Under constant-current conditions, pH values ranging from 1.68 to 9.18 can be determined more quickly and stably than with conventional methods that depend on the proton selectivity of glass electrodes under equilibrium conditions. Nature Publishing Group UK 2020-03-05 /pmc/articles/PMC7058011/ /pubmed/32139704 http://dx.doi.org/10.1038/s41598-020-60713-z Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Doi, Kentaro Asano, Naoki Kawano, Satoyuki Development of glass micro-electrodes for local electric field, electrical conductivity, and pH measurements |
title | Development of glass micro-electrodes for local electric field, electrical conductivity, and pH measurements |
title_full | Development of glass micro-electrodes for local electric field, electrical conductivity, and pH measurements |
title_fullStr | Development of glass micro-electrodes for local electric field, electrical conductivity, and pH measurements |
title_full_unstemmed | Development of glass micro-electrodes for local electric field, electrical conductivity, and pH measurements |
title_short | Development of glass micro-electrodes for local electric field, electrical conductivity, and pH measurements |
title_sort | development of glass micro-electrodes for local electric field, electrical conductivity, and ph measurements |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058011/ https://www.ncbi.nlm.nih.gov/pubmed/32139704 http://dx.doi.org/10.1038/s41598-020-60713-z |
work_keys_str_mv | AT doikentaro developmentofglassmicroelectrodesforlocalelectricfieldelectricalconductivityandphmeasurements AT asanonaoki developmentofglassmicroelectrodesforlocalelectricfieldelectricalconductivityandphmeasurements AT kawanosatoyuki developmentofglassmicroelectrodesforlocalelectricfieldelectricalconductivityandphmeasurements |