Exploring the role of the Ser9Gly (rs6280) Dopamine D3 receptor polymorphism in nicotine reinforcement and cue-elicited craving

Preclinical studies show that the dopamine D3 receptor (D3R) is involved in the reinstatement of drug seeking and motivation for drugs of abuse. A D3R gene variant, Ser9Gly (rs6280) has been linked to nicotine dependence, yet the mechanisms underlying its involvement in nicotine dependence is unclea...

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Detalles Bibliográficos
Autores principales: Chukwueke, Chidera C., Kowalczyk, William J., Di Ciano, Patricia, Gendy, Marie, Taylor, Richard, Heishman, Stephen J., Le Foll, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058013/
https://www.ncbi.nlm.nih.gov/pubmed/32139730
http://dx.doi.org/10.1038/s41598-020-60940-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058013/
https://www.ncbi.nlm.nih.gov/pubmed/32139730
http://dx.doi.org/10.1038/s41598-020-60940-4

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