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Temporal changes in the gene expression heterogeneity during brain development and aging
Cells in largely non-mitotic tissues such as the brain are prone to stochastic (epi-)genetic alterations that may cause increased variability between cells and individuals over time. Although increased inter-individual heterogeneity in gene expression was previously reported, whether this process st...
Autores principales: | Işıldak, Ulaş, Somel, Mehmet, Thornton, Janet M., Dönertaş, Handan Melike |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058021/ https://www.ncbi.nlm.nih.gov/pubmed/32139741 http://dx.doi.org/10.1038/s41598-020-60998-0 |
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