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CHD Risk Minimization through Lifestyle Control: Machine Learning Gateway

Studies on the influence of a modern lifestyle in abetting Coronary Heart Diseases (CHD) have mostly focused on deterrent health factors, like smoking, alcohol intake, cheese consumption and average systolic blood pressure, largely disregarding the impact of a healthy lifestyle in mitigating CHD ris...

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Autores principales: He, Xi, Matam, B. Rajeswari, Bellary, Srikanth, Ghosh, Goutam, Chattopadhyay, Amit K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058059/
https://www.ncbi.nlm.nih.gov/pubmed/32139725
http://dx.doi.org/10.1038/s41598-020-60786-w
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author He, Xi
Matam, B. Rajeswari
Bellary, Srikanth
Ghosh, Goutam
Chattopadhyay, Amit K.
author_facet He, Xi
Matam, B. Rajeswari
Bellary, Srikanth
Ghosh, Goutam
Chattopadhyay, Amit K.
author_sort He, Xi
collection PubMed
description Studies on the influence of a modern lifestyle in abetting Coronary Heart Diseases (CHD) have mostly focused on deterrent health factors, like smoking, alcohol intake, cheese consumption and average systolic blood pressure, largely disregarding the impact of a healthy lifestyle in mitigating CHD risk. In this study, 30+ years' World Health Organization (WHO) data have been analyzed, using a wide array of advanced Machine Learning techniques, to quantify how regulated reliance on positive health indicators, e.g. fruits/vegetables, cereals can offset CHD risk factors over a period of time. Our research ranks the impact of the negative outliers on CHD and then quantifies the impact of the positive health factors in mitigating the negative risk-factors. Our research outcomes, presented through simple mathematical equations, outline the best CHD prevention strategy using lifestyle control only. We show that a 20% increase in the intake of fruit/vegetable leads to 3–6% decrease in SBP; or, a 10% increase in cereal intake lowers SBP by 3%; a simultaneous increase of 10% in fruit-vegetable can further offset the effects of SBP by 6%. Our analysis establishes gender independence of lifestyle on CHD, refuting long held assumptions and unqualified beliefs. We show that CHD risk can be lowered with incremental changes in lifestyle and diet, e.g. fruit-vegetable intake ameliorating effects of alcohol-smoking-fatty food. Our multivariate data model also estimates functional relationships amongst lifestyle factors that can potentially redefine the diagnostics of Framingham score-based CHD-prediction.
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spelling pubmed-70580592020-03-12 CHD Risk Minimization through Lifestyle Control: Machine Learning Gateway He, Xi Matam, B. Rajeswari Bellary, Srikanth Ghosh, Goutam Chattopadhyay, Amit K. Sci Rep Article Studies on the influence of a modern lifestyle in abetting Coronary Heart Diseases (CHD) have mostly focused on deterrent health factors, like smoking, alcohol intake, cheese consumption and average systolic blood pressure, largely disregarding the impact of a healthy lifestyle in mitigating CHD risk. In this study, 30+ years' World Health Organization (WHO) data have been analyzed, using a wide array of advanced Machine Learning techniques, to quantify how regulated reliance on positive health indicators, e.g. fruits/vegetables, cereals can offset CHD risk factors over a period of time. Our research ranks the impact of the negative outliers on CHD and then quantifies the impact of the positive health factors in mitigating the negative risk-factors. Our research outcomes, presented through simple mathematical equations, outline the best CHD prevention strategy using lifestyle control only. We show that a 20% increase in the intake of fruit/vegetable leads to 3–6% decrease in SBP; or, a 10% increase in cereal intake lowers SBP by 3%; a simultaneous increase of 10% in fruit-vegetable can further offset the effects of SBP by 6%. Our analysis establishes gender independence of lifestyle on CHD, refuting long held assumptions and unqualified beliefs. We show that CHD risk can be lowered with incremental changes in lifestyle and diet, e.g. fruit-vegetable intake ameliorating effects of alcohol-smoking-fatty food. Our multivariate data model also estimates functional relationships amongst lifestyle factors that can potentially redefine the diagnostics of Framingham score-based CHD-prediction. Nature Publishing Group UK 2020-03-05 /pmc/articles/PMC7058059/ /pubmed/32139725 http://dx.doi.org/10.1038/s41598-020-60786-w Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
He, Xi
Matam, B. Rajeswari
Bellary, Srikanth
Ghosh, Goutam
Chattopadhyay, Amit K.
CHD Risk Minimization through Lifestyle Control: Machine Learning Gateway
title CHD Risk Minimization through Lifestyle Control: Machine Learning Gateway
title_full CHD Risk Minimization through Lifestyle Control: Machine Learning Gateway
title_fullStr CHD Risk Minimization through Lifestyle Control: Machine Learning Gateway
title_full_unstemmed CHD Risk Minimization through Lifestyle Control: Machine Learning Gateway
title_short CHD Risk Minimization through Lifestyle Control: Machine Learning Gateway
title_sort chd risk minimization through lifestyle control: machine learning gateway
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058059/
https://www.ncbi.nlm.nih.gov/pubmed/32139725
http://dx.doi.org/10.1038/s41598-020-60786-w
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