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Pathogen transmission from vaccinated hosts can cause dose-dependent reduction in virulence

Many livestock and human vaccines are leaky because they block symptoms but do not prevent infection or onward transmission. This leakiness is concerning because it increases vaccination coverage required to prevent disease spread and can promote evolution of increased pathogen virulence. Despite le...

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Detalles Bibliográficos
Autores principales: Bailey, Richard I., Cheng, Hans H., Chase-Topping, Margo, Mays, Jody K., Anacleto, Osvaldo, Dunn, John R., Doeschl-Wilson, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058279/
https://www.ncbi.nlm.nih.gov/pubmed/32134914
http://dx.doi.org/10.1371/journal.pbio.3000619

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