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Angiotensin II triggers RIPK3-MLKL-mediated necroptosis by activating the Fas/FasL signaling pathway in renal tubular cells

Our earlier studies proved that RIPK3-mediated necroptosis might be an important mode of renal tubular cell death in rats with chronic renal injury and the necroptotic cell death can be triggered by tumor necrosis factor-α (TNF-α) in vitro, but the triggering role of angiotensin II (AngII), which ex...

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Detalles Bibliográficos
Autores principales: Zhu, Yongjun, Cui, Hongwang, Lv, Jie, Li, Guojun, Li, Xiaoyan, Ye, Feng, Zhong, Liangbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058379/
https://www.ncbi.nlm.nih.gov/pubmed/32134954
http://dx.doi.org/10.1371/journal.pone.0228385