Biophysicochemical motifs in T cell receptor sequences as a potential biomarker for high-grade serous ovarian carcinoma

We previously showed, in a pilot study with publicly available data, that T cell receptor (TCR) repertoires from tumor infiltrating lymphocytes (TILs) could be distinguished from adjacent healthy tissue repertoires by the presence of TCRs bearing specific, biophysicochemical motifs in their antigen...

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Detalles Bibliográficos
Autores principales: Ostmeyer, Jared, Lucas, Elena, Christley, Scott, Lea, Jayanthi, Monson, Nancy, Tiro, Jasmin, Cowell, Lindsay G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058380/
https://www.ncbi.nlm.nih.gov/pubmed/32134923
http://dx.doi.org/10.1371/journal.pone.0229569

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