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Temozolomide and Pazopanib Combined with FOLFOX Regressed a Primary Colorectal Cancer in a Patient-derived Orthotopic Xenograft Mouse Model

Purpose: The goal of the present study was to determine the efficacy of temozolomide (TEM) and pazopanib (PAZ) combined with FOLFOX (oxaliplatin, leucovorin and 5-fluorouracil) on a colorectal cancer patient-derived orthotopic xenograft (PDOX) mouse model. Materials and Methods: A colorectal cancer...

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Detalles Bibliográficos
Autores principales: Zhu, Guangwei, Zhao, Ming, Han, Qinghong, Tan, Yuying, Sun, Yu, Bouvet, Michael, Clary, Bryan, Singh, Shree Ram, Ye, Jianxin, Hoffman, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058405/
https://www.ncbi.nlm.nih.gov/pubmed/32143177
http://dx.doi.org/10.1016/j.tranon.2019.12.011