Epigenetics in age-related macular degeneration: new discoveries and future perspectives

The study of epigenetics has explained some of the ‘missing heritability’ of age-related macular degeneration (AMD). The epigenome also provides a substantial contribution to the organisation of the functional retina. There is emerging evidence of specific epigenetic mechanisms associated with AMD....

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Detalles Bibliográficos
Autores principales: Gemenetzi, M., Lotery, A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058675/
https://www.ncbi.nlm.nih.gov/pubmed/31897542
http://dx.doi.org/10.1007/s00018-019-03421-w
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author Gemenetzi, M.
Lotery, A. J.
author_facet Gemenetzi, M.
Lotery, A. J.
author_sort Gemenetzi, M.
collection PubMed
description The study of epigenetics has explained some of the ‘missing heritability’ of age-related macular degeneration (AMD). The epigenome also provides a substantial contribution to the organisation of the functional retina. There is emerging evidence of specific epigenetic mechanisms associated with AMD. This ‘AMD epigenome’ may offer the chance to develop novel AMD treatments.
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spelling pubmed-70586752020-03-16 Epigenetics in age-related macular degeneration: new discoveries and future perspectives Gemenetzi, M. Lotery, A. J. Cell Mol Life Sci Review The study of epigenetics has explained some of the ‘missing heritability’ of age-related macular degeneration (AMD). The epigenome also provides a substantial contribution to the organisation of the functional retina. There is emerging evidence of specific epigenetic mechanisms associated with AMD. This ‘AMD epigenome’ may offer the chance to develop novel AMD treatments. Springer International Publishing 2020-01-02 2020 /pmc/articles/PMC7058675/ /pubmed/31897542 http://dx.doi.org/10.1007/s00018-019-03421-w Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Review
Gemenetzi, M.
Lotery, A. J.
Epigenetics in age-related macular degeneration: new discoveries and future perspectives
title Epigenetics in age-related macular degeneration: new discoveries and future perspectives
title_full Epigenetics in age-related macular degeneration: new discoveries and future perspectives
title_fullStr Epigenetics in age-related macular degeneration: new discoveries and future perspectives
title_full_unstemmed Epigenetics in age-related macular degeneration: new discoveries and future perspectives
title_short Epigenetics in age-related macular degeneration: new discoveries and future perspectives
title_sort epigenetics in age-related macular degeneration: new discoveries and future perspectives
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058675/
https://www.ncbi.nlm.nih.gov/pubmed/31897542
http://dx.doi.org/10.1007/s00018-019-03421-w
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