Cargando…

Immunomodulation for maxillofacial reconstructive surgery

Immunomodulation is a technique for the modulation of immune responses against graft material to improve surgical success rates. The main target cell for the immunomodulation is a macrophage because it is the reaction site of the graft and controls the healing process. Macrophages can be classified...

Descripción completa

Detalles Bibliográficos
Autor principal: Kim, Seong-Gon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058765/
https://www.ncbi.nlm.nih.gov/pubmed/32206664
http://dx.doi.org/10.1186/s40902-020-00249-4
_version_ 1783503916878528512
author Kim, Seong-Gon
author_facet Kim, Seong-Gon
author_sort Kim, Seong-Gon
collection PubMed
description Immunomodulation is a technique for the modulation of immune responses against graft material to improve surgical success rates. The main target cell for the immunomodulation is a macrophage because it is the reaction site of the graft and controls the healing process. Macrophages can be classified into M1 and M2 types. Most immunomodulation techniques focus on the rapid differentiation of M2-type macrophage. An M2 inducer, 4-hexylresorcinol, has been recently identified and is used for bone grafts and dental implant coatings.
format Online
Article
Text
id pubmed-7058765
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Springer Singapore
record_format MEDLINE/PubMed
spelling pubmed-70587652020-03-23 Immunomodulation for maxillofacial reconstructive surgery Kim, Seong-Gon Maxillofac Plast Reconstr Surg Review Immunomodulation is a technique for the modulation of immune responses against graft material to improve surgical success rates. The main target cell for the immunomodulation is a macrophage because it is the reaction site of the graft and controls the healing process. Macrophages can be classified into M1 and M2 types. Most immunomodulation techniques focus on the rapid differentiation of M2-type macrophage. An M2 inducer, 4-hexylresorcinol, has been recently identified and is used for bone grafts and dental implant coatings. Springer Singapore 2020-03-05 /pmc/articles/PMC7058765/ /pubmed/32206664 http://dx.doi.org/10.1186/s40902-020-00249-4 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Review
Kim, Seong-Gon
Immunomodulation for maxillofacial reconstructive surgery
title Immunomodulation for maxillofacial reconstructive surgery
title_full Immunomodulation for maxillofacial reconstructive surgery
title_fullStr Immunomodulation for maxillofacial reconstructive surgery
title_full_unstemmed Immunomodulation for maxillofacial reconstructive surgery
title_short Immunomodulation for maxillofacial reconstructive surgery
title_sort immunomodulation for maxillofacial reconstructive surgery
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058765/
https://www.ncbi.nlm.nih.gov/pubmed/32206664
http://dx.doi.org/10.1186/s40902-020-00249-4
work_keys_str_mv AT kimseonggon immunomodulationformaxillofacialreconstructivesurgery