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Immunomodulation for maxillofacial reconstructive surgery
Immunomodulation is a technique for the modulation of immune responses against graft material to improve surgical success rates. The main target cell for the immunomodulation is a macrophage because it is the reaction site of the graft and controls the healing process. Macrophages can be classified...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Singapore
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058765/ https://www.ncbi.nlm.nih.gov/pubmed/32206664 http://dx.doi.org/10.1186/s40902-020-00249-4 |
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author | Kim, Seong-Gon |
author_facet | Kim, Seong-Gon |
author_sort | Kim, Seong-Gon |
collection | PubMed |
description | Immunomodulation is a technique for the modulation of immune responses against graft material to improve surgical success rates. The main target cell for the immunomodulation is a macrophage because it is the reaction site of the graft and controls the healing process. Macrophages can be classified into M1 and M2 types. Most immunomodulation techniques focus on the rapid differentiation of M2-type macrophage. An M2 inducer, 4-hexylresorcinol, has been recently identified and is used for bone grafts and dental implant coatings. |
format | Online Article Text |
id | pubmed-7058765 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Springer Singapore |
record_format | MEDLINE/PubMed |
spelling | pubmed-70587652020-03-23 Immunomodulation for maxillofacial reconstructive surgery Kim, Seong-Gon Maxillofac Plast Reconstr Surg Review Immunomodulation is a technique for the modulation of immune responses against graft material to improve surgical success rates. The main target cell for the immunomodulation is a macrophage because it is the reaction site of the graft and controls the healing process. Macrophages can be classified into M1 and M2 types. Most immunomodulation techniques focus on the rapid differentiation of M2-type macrophage. An M2 inducer, 4-hexylresorcinol, has been recently identified and is used for bone grafts and dental implant coatings. Springer Singapore 2020-03-05 /pmc/articles/PMC7058765/ /pubmed/32206664 http://dx.doi.org/10.1186/s40902-020-00249-4 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Review Kim, Seong-Gon Immunomodulation for maxillofacial reconstructive surgery |
title | Immunomodulation for maxillofacial reconstructive surgery |
title_full | Immunomodulation for maxillofacial reconstructive surgery |
title_fullStr | Immunomodulation for maxillofacial reconstructive surgery |
title_full_unstemmed | Immunomodulation for maxillofacial reconstructive surgery |
title_short | Immunomodulation for maxillofacial reconstructive surgery |
title_sort | immunomodulation for maxillofacial reconstructive surgery |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058765/ https://www.ncbi.nlm.nih.gov/pubmed/32206664 http://dx.doi.org/10.1186/s40902-020-00249-4 |
work_keys_str_mv | AT kimseonggon immunomodulationformaxillofacialreconstructivesurgery |