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Regulation of Microbial Metabolic Rates Using CRISPR Interference With Expanded PAM Sequences
Genome-editing CRISPR/Cas9 technology has led to the development of artificial transcriptional repressors, also known as CRISPR interference (CRISPRi). The deactivated Cas9 (dCas9) protein guided by crRNA can specifically bind to target DNA sequences, including promoters and operators, without DNA c...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058998/ https://www.ncbi.nlm.nih.gov/pubmed/32184769 http://dx.doi.org/10.3389/fmicb.2020.00282 |