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Dysregulated mesenchymal PDGFR‐β drives kidney fibrosis
Kidney fibrosis is characterized by expansion and activation of platelet‐derived growth factor receptor‐β (PDGFR‐β)‐positive mesenchymal cells. To study the consequences of PDGFR‐β activation, we developed a model of primary renal fibrosis using transgenic mice with PDGFR‐β activation specifically i...
Autores principales: | Buhl, Eva M, Djudjaj, Sonja, Klinkhammer, Barbara M, Ermert, Katja, Puelles, Victor G, Lindenmeyer, Maja T, Cohen, Clemens D, He, Chaoyong, Borkham‐Kamphorst, Erawan, Weiskirchen, Ralf, Denecke, Bernd, Trairatphisan, Panuwat, Saez‐Rodriguez, Julio, Huber, Tobias B, Olson, Lorin E, Floege, Jürgen, Boor, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059015/ https://www.ncbi.nlm.nih.gov/pubmed/31943786 http://dx.doi.org/10.15252/emmm.201911021 |
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