Cargando…
The Volatile Chemical Compositions of the Essential Oil/SPME and Enzyme Inhibitory and Radical Scavenging Activities of Solvent Extracts and the Essential oils from Coronilla orientalis Miller and C. varia L. grows in Turkey
The volatile organic compounds (VOCs) of two Coronilla species (Coronilla orientalis Miller and Coronilla varia L.) obtained by hydrodistillation (HD) and solid phase microextraction (SPME) techniques were identified by GC-FID/MS. The major compounds identified in the SPME extracts were limonene (43...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shaheed Beheshti University of Medical Sciences
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059027/ https://www.ncbi.nlm.nih.gov/pubmed/32184850 http://dx.doi.org/10.22037/ijpr.2019.1100802 |
_version_ | 1783503964432498688 |
---|---|
author | Renda, Gülin Özel, Arzu Barut, Burak Korkmaz, Büşra Yayli, Nurettin |
author_facet | Renda, Gülin Özel, Arzu Barut, Burak Korkmaz, Büşra Yayli, Nurettin |
author_sort | Renda, Gülin |
collection | PubMed |
description | The volatile organic compounds (VOCs) of two Coronilla species (Coronilla orientalis Miller and Coronilla varia L.) obtained by hydrodistillation (HD) and solid phase microextraction (SPME) techniques were identified by GC-FID/MS. The major compounds identified in the SPME extracts were limonene (43.4%) in Coronilla orientalis (C. orientalis), (Z)-β-ocimene and (E)-β-ocimene (34.3% and 32.4%) in Coronilla varia (C. varia), whereas, the essential oils of C. orientalis and C. varia were rich with γ-terpinene (22.4%) and phytol (30.7%), respectively. In addition, acetylcholinesterase (AChE), butyrylcholinesterase (BuChE), tyrosinase, α-glucosidase enzyme inhibitory, and radical scavenging activities (DPPH) of chloroform, ethyl acetate, methanol, and water extracts, and also essential oils obtained from C. orientalis and C. varia were investigated. The tyrosinase activity was studied at the doses of 25 µg/mL, 50 µg/mL and 100 µg/mL. Tyrosinase inhibition percentage was observed to increase by dose and methanol extracts of the both species were found to have the highest activity. Essential oils of the both species were found to have significant acetylcholinesterase and butyrylcholinesterase inhibition activities. α-Glucosidase enzyme inhibition of the ethyl acetate and water extracts of C. orientalis was determined as 80.11 ± 4.07% and 80.32 ± 3.47% at the 100 µg/mL concentration, respectively. Essential oils, chloroform, ethyl acetate, methanol, and water extracts were determined to have moderate DPPH radical scavenging activities. |
format | Online Article Text |
id | pubmed-7059027 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Shaheed Beheshti University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-70590272020-03-17 The Volatile Chemical Compositions of the Essential Oil/SPME and Enzyme Inhibitory and Radical Scavenging Activities of Solvent Extracts and the Essential oils from Coronilla orientalis Miller and C. varia L. grows in Turkey Renda, Gülin Özel, Arzu Barut, Burak Korkmaz, Büşra Yayli, Nurettin Iran J Pharm Res Original Article The volatile organic compounds (VOCs) of two Coronilla species (Coronilla orientalis Miller and Coronilla varia L.) obtained by hydrodistillation (HD) and solid phase microextraction (SPME) techniques were identified by GC-FID/MS. The major compounds identified in the SPME extracts were limonene (43.4%) in Coronilla orientalis (C. orientalis), (Z)-β-ocimene and (E)-β-ocimene (34.3% and 32.4%) in Coronilla varia (C. varia), whereas, the essential oils of C. orientalis and C. varia were rich with γ-terpinene (22.4%) and phytol (30.7%), respectively. In addition, acetylcholinesterase (AChE), butyrylcholinesterase (BuChE), tyrosinase, α-glucosidase enzyme inhibitory, and radical scavenging activities (DPPH) of chloroform, ethyl acetate, methanol, and water extracts, and also essential oils obtained from C. orientalis and C. varia were investigated. The tyrosinase activity was studied at the doses of 25 µg/mL, 50 µg/mL and 100 µg/mL. Tyrosinase inhibition percentage was observed to increase by dose and methanol extracts of the both species were found to have the highest activity. Essential oils of the both species were found to have significant acetylcholinesterase and butyrylcholinesterase inhibition activities. α-Glucosidase enzyme inhibition of the ethyl acetate and water extracts of C. orientalis was determined as 80.11 ± 4.07% and 80.32 ± 3.47% at the 100 µg/mL concentration, respectively. Essential oils, chloroform, ethyl acetate, methanol, and water extracts were determined to have moderate DPPH radical scavenging activities. Shaheed Beheshti University of Medical Sciences 2019 /pmc/articles/PMC7059027/ /pubmed/32184850 http://dx.doi.org/10.22037/ijpr.2019.1100802 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Renda, Gülin Özel, Arzu Barut, Burak Korkmaz, Büşra Yayli, Nurettin The Volatile Chemical Compositions of the Essential Oil/SPME and Enzyme Inhibitory and Radical Scavenging Activities of Solvent Extracts and the Essential oils from Coronilla orientalis Miller and C. varia L. grows in Turkey |
title | The Volatile Chemical Compositions of the Essential Oil/SPME and Enzyme Inhibitory and Radical Scavenging Activities of Solvent Extracts and the Essential oils from Coronilla orientalis Miller and C. varia L. grows in Turkey |
title_full | The Volatile Chemical Compositions of the Essential Oil/SPME and Enzyme Inhibitory and Radical Scavenging Activities of Solvent Extracts and the Essential oils from Coronilla orientalis Miller and C. varia L. grows in Turkey |
title_fullStr | The Volatile Chemical Compositions of the Essential Oil/SPME and Enzyme Inhibitory and Radical Scavenging Activities of Solvent Extracts and the Essential oils from Coronilla orientalis Miller and C. varia L. grows in Turkey |
title_full_unstemmed | The Volatile Chemical Compositions of the Essential Oil/SPME and Enzyme Inhibitory and Radical Scavenging Activities of Solvent Extracts and the Essential oils from Coronilla orientalis Miller and C. varia L. grows in Turkey |
title_short | The Volatile Chemical Compositions of the Essential Oil/SPME and Enzyme Inhibitory and Radical Scavenging Activities of Solvent Extracts and the Essential oils from Coronilla orientalis Miller and C. varia L. grows in Turkey |
title_sort | volatile chemical compositions of the essential oil/spme and enzyme inhibitory and radical scavenging activities of solvent extracts and the essential oils from coronilla orientalis miller and c. varia l. grows in turkey |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059027/ https://www.ncbi.nlm.nih.gov/pubmed/32184850 http://dx.doi.org/10.22037/ijpr.2019.1100802 |
work_keys_str_mv | AT rendagulin thevolatilechemicalcompositionsoftheessentialoilspmeandenzymeinhibitoryandradicalscavengingactivitiesofsolventextractsandtheessentialoilsfromcoronillaorientalismillerandcvarialgrowsinturkey AT ozelarzu thevolatilechemicalcompositionsoftheessentialoilspmeandenzymeinhibitoryandradicalscavengingactivitiesofsolventextractsandtheessentialoilsfromcoronillaorientalismillerandcvarialgrowsinturkey AT barutburak thevolatilechemicalcompositionsoftheessentialoilspmeandenzymeinhibitoryandradicalscavengingactivitiesofsolventextractsandtheessentialoilsfromcoronillaorientalismillerandcvarialgrowsinturkey AT korkmazbusra thevolatilechemicalcompositionsoftheessentialoilspmeandenzymeinhibitoryandradicalscavengingactivitiesofsolventextractsandtheessentialoilsfromcoronillaorientalismillerandcvarialgrowsinturkey AT yaylinurettin thevolatilechemicalcompositionsoftheessentialoilspmeandenzymeinhibitoryandradicalscavengingactivitiesofsolventextractsandtheessentialoilsfromcoronillaorientalismillerandcvarialgrowsinturkey AT rendagulin volatilechemicalcompositionsoftheessentialoilspmeandenzymeinhibitoryandradicalscavengingactivitiesofsolventextractsandtheessentialoilsfromcoronillaorientalismillerandcvarialgrowsinturkey AT ozelarzu volatilechemicalcompositionsoftheessentialoilspmeandenzymeinhibitoryandradicalscavengingactivitiesofsolventextractsandtheessentialoilsfromcoronillaorientalismillerandcvarialgrowsinturkey AT barutburak volatilechemicalcompositionsoftheessentialoilspmeandenzymeinhibitoryandradicalscavengingactivitiesofsolventextractsandtheessentialoilsfromcoronillaorientalismillerandcvarialgrowsinturkey AT korkmazbusra volatilechemicalcompositionsoftheessentialoilspmeandenzymeinhibitoryandradicalscavengingactivitiesofsolventextractsandtheessentialoilsfromcoronillaorientalismillerandcvarialgrowsinturkey AT yaylinurettin volatilechemicalcompositionsoftheessentialoilspmeandenzymeinhibitoryandradicalscavengingactivitiesofsolventextractsandtheessentialoilsfromcoronillaorientalismillerandcvarialgrowsinturkey |