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Effect of Topiramate on Morphine-induced Conditioned Place Preference (CPP) in Rats: Role of ERK and CREB Proteins in Hippocampus and Cerebral Cortex

In this study, the effect of topiramate, as an antiepileptic drug, was evaluated on morphine craving in rats. The conditioned place preference (CPP) test was used for this purpose. Repeated administration of morphine (10 mg/kg, i.p. for 4 days) induced significant CPP. Administration of topiramate (...

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Detalles Bibliográficos
Autores principales: Bagherpasand, Nima, Mehri, Soghra, Jafari Shahroudi, Mahdieh, Tabatabai, Seyed Meghdad, Khezri, Ali, Fathi, Mohammad, Abnous, Khalil, Imenshahidi, Mohsen, Hosseinzadeh, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059042/
https://www.ncbi.nlm.nih.gov/pubmed/32184865
http://dx.doi.org/10.22037/ijpr.2019.1100873