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Novel 5-(nitrothiophene-2-yl)-1,3,4-Thiadiazole Derivatives: Synthesis and Antileishmanial Activity against promastigote stage of Leishmania major

In this study, a series of novel compounds based on 5-(5-nitrothiophene-2-yl)-1,3,4-thiadiazole possessing (het) aryl thio pendant at C-2 position of thiadiazole ring is developed and evaluated as antileishmanial agents using MTT colorimetric assay. 10 New compounds containing aryl and heteroaryl de...

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Detalles Bibliográficos
Autores principales: Sadat-Ebrahimi, Seyed Esmail, Mirmohammadi, Maryam, Mojallal Tabatabaei, Zahra, Azimzadeh Arani, Marjan, Jafari-Ashtiani, Sogol, Hashemian, Mahsa, Foroumadi, Parham, Yahya-Meymandi, Azadeh, Moghimi, Setareh, Moshafi, Mohammad Hassan, Norouzi, Peiman, Kabudanian Ardestani, Susan, Foroumadi, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059068/
https://www.ncbi.nlm.nih.gov/pubmed/32184848
http://dx.doi.org/10.22037/ijpr.2019.14547.12476