Allogeneic Hematopoietic Stem Cell Transplantation in a Rare Case of Tonsillar Mast Cell Sarcoma

Mast cell sarcoma comprises a rare aggressive mast cell neoplasia with histological, clinical, and genetic features distinct from other mast cell neoplasm. Until now, prognosis is still poor due to high rates of progression to mast cell leukemia and failure of conventional chemotherapies. Our here p...

Descripción completa

Detalles Bibliográficos
Autores principales: Kubasch, Anne Sophie, Franke, Georg-Nikolaus, Aldaoud, Ali, Weibl, Konstantin, Jentzsch, Madlen, Sabri, Osama, Horny, Hans-Peter, Fend, Falko, Behre, Gerhard, Platzbecker, Uwe, Vucinic, Vladan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059127/
https://www.ncbi.nlm.nih.gov/pubmed/32181155
http://dx.doi.org/10.3389/fonc.2020.00219
Descripción
Sumario:Mast cell sarcoma comprises a rare aggressive mast cell neoplasia with histological, clinical, and genetic features distinct from other mast cell neoplasm. Until now, prognosis is still poor due to high rates of progression to mast cell leukemia and failure of conventional chemotherapies. Our here presented first report about successful allogeneic hematopoietic stem cell transplantation leading to remission in a case of tonsillar MCS represents a promising potential curative treatment option for this rare and often fatal disease.

Ejemplares similares