Mitochondrial function in skeletal myofibers is controlled by a TRF2‐SIRT3 axis over lifetime

Telomere shortening follows a developmentally regulated process that leads to replicative senescence of dividing cells. However, whether telomere changes are involved in postmitotic cell function and aging remains elusive. In this study, we discovered that the level of the TRF2 protein, a key telome...

Descripción completa

Detalles Bibliográficos
Autores principales: Robin, Jérôme D., Jacome Burbano, Maria‐Sol, Peng, Han, Croce, Olivier, Thomas, Jean Luc, Laberthonniere, Camille, Renault, Valerie, Lototska, Liudmyla, Pousse, Mélanie, Tessier, Florent, Bauwens, Serge, Leong, Waiian, Sacconi, Sabrina, Schaeffer, Laurent, Magdinier, Frédérique, Ye, Jing, Gilson, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059141/
https://www.ncbi.nlm.nih.gov/pubmed/31991048
http://dx.doi.org/10.1111/acel.13097

Ejemplares similares

Ejemplares similares