Increased miR‐34c mediates synaptic deficits by targeting synaptotagmin 1 through ROS‐JNK‐p53 pathway in Alzheimer’s Disease

Alzheimer's disease (AD) and cancer have inverse relationship in many aspects. Some tumor suppressors, including miR‐34c, are decreased in cancer but increased in AD. The upstream regulatory pathways and the downstream mechanisms of miR‐34c in AD remain to be investigated. The expression of miR...

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Detalles Bibliográficos
Autores principales: Shi, Zhongli, Zhang, Kaixia, Zhou, Huimin, Jiang, Lei, Xie, Bing, Wang, Ruiyuan, Xia, Wenzhen, Yin, Yajuan, Gao, Zhaoyu, Cui, Dongsheng, Zhang, Rui, Xu, Shunjiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059146/
https://www.ncbi.nlm.nih.gov/pubmed/32092796
http://dx.doi.org/10.1111/acel.13125

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