Mobilization‐based transplantation of young‐donor hematopoietic stem cells extends lifespan in mice

Mammalian aging is associated with reduced tissue regeneration and loss of physiological integrity. With age, stem cells diminish in their ability to regenerate adult tissues, likely contributing to age‐related morbidity. Thus, we replaced aged hematopoietic stem cells (HSCs) with young‐donor HSCs u...

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Detalles Bibliográficos
Autores principales: Guderyon, Michael J., Chen, Cang, Bhattacharjee, Anindita, Ge, Guo, Fernandez, Roman A., Gelfond, Jonathan A. L., Gorena, Karla M., Cheng, Catherine J., Li, Yang, Nelson, James F., Strong, Randy J., Hornsby, Peter J., Clark, Robert A., Li, Senlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059148/
https://www.ncbi.nlm.nih.gov/pubmed/32012439
http://dx.doi.org/10.1111/acel.13110

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