Molecular Mechanisms of PALB2 Function and Its Role in Breast Cancer Management

Partner and localizer of BRCA2 (PALB2) is vital for homologous recombination (HR) repair in response to DNA double-strand breaks (DSBs). PALB2 functions as a tumor suppressor and participates in the maintenance of genome integrity. In this review, we summarize the current knowledge of the biological...

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Detalles Bibliográficos
Autores principales: Wu, Shijie, Zhou, Jiaojiao, Zhang, Kun, Chen, Huihui, Luo, Meng, Lu, Yuexin, Sun, Yuting, Chen, Yiding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059202/
https://www.ncbi.nlm.nih.gov/pubmed/32185139
http://dx.doi.org/10.3389/fonc.2020.00301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059202/
https://www.ncbi.nlm.nih.gov/pubmed/32185139
http://dx.doi.org/10.3389/fonc.2020.00301

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