Ultrasonic-assisted unusual four-component synthesis of 7-azolylamino-4,5,6,7-tetrahydroazolo[1,5-a]pyrimidines

Four-component reactions of 3-amino-1,2,4-triazole or 5-amino-1H-pyrazole-4-carbonitrile with aromatic aldehydes and pyruvic acid or its esters under ultrasonication were studied. Unusual for such a reaction type, a cascade of elementary stages led to the formation of 7-azolylaminotetrahydroazolo[1,...

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Detalles Bibliográficos
Autores principales: Sakhno, Yana I, Murlykina, Maryna V, Zbruyev, Oleksandr I, Kozyryev, Anton V, Shishkina, Svetlana V, Sysoiev, Dmytro, Musatov, Vladimir I, Desenko, Sergey M, Chebanov, Valentyn A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2020
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059450/
https://www.ncbi.nlm.nih.gov/pubmed/32180844
http://dx.doi.org/10.3762/bjoc.16.27
Descripción
Sumario:Four-component reactions of 3-amino-1,2,4-triazole or 5-amino-1H-pyrazole-4-carbonitrile with aromatic aldehydes and pyruvic acid or its esters under ultrasonication were studied. Unusual for such a reaction type, a cascade of elementary stages led to the formation of 7-azolylaminotetrahydroazolo[1,5-a]pyrimidines.

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