Ultrasonic-assisted unusual four-component synthesis of 7-azolylamino-4,5,6,7-tetrahydroazolo[1,5-a]pyrimidines

Four-component reactions of 3-amino-1,2,4-triazole or 5-amino-1H-pyrazole-4-carbonitrile with aromatic aldehydes and pyruvic acid or its esters under ultrasonication were studied. Unusual for such a reaction type, a cascade of elementary stages led to the formation of 7-azolylaminotetrahydroazolo[1,...

Descripción completa

Detalles Bibliográficos
Autores principales: Sakhno, Yana I, Murlykina, Maryna V, Zbruyev, Oleksandr I, Kozyryev, Anton V, Shishkina, Svetlana V, Sysoiev, Dmytro, Musatov, Vladimir I, Desenko, Sergey M, Chebanov, Valentyn A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2020
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059450/
https://www.ncbi.nlm.nih.gov/pubmed/32180844
http://dx.doi.org/10.3762/bjoc.16.27
_version_ 1783504052526514176
author Sakhno, Yana I
Murlykina, Maryna V
Zbruyev, Oleksandr I
Kozyryev, Anton V
Shishkina, Svetlana V
Sysoiev, Dmytro
Musatov, Vladimir I
Desenko, Sergey M
Chebanov, Valentyn A
author_facet Sakhno, Yana I
Murlykina, Maryna V
Zbruyev, Oleksandr I
Kozyryev, Anton V
Shishkina, Svetlana V
Sysoiev, Dmytro
Musatov, Vladimir I
Desenko, Sergey M
Chebanov, Valentyn A
author_sort Sakhno, Yana I
collection PubMed
description Four-component reactions of 3-amino-1,2,4-triazole or 5-amino-1H-pyrazole-4-carbonitrile with aromatic aldehydes and pyruvic acid or its esters under ultrasonication were studied. Unusual for such a reaction type, a cascade of elementary stages led to the formation of 7-azolylaminotetrahydroazolo[1,5-a]pyrimidines.
format Online
Article
Text
id pubmed-7059450
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Beilstein-Institut
record_format MEDLINE/PubMed
spelling pubmed-70594502020-03-16 Ultrasonic-assisted unusual four-component synthesis of 7-azolylamino-4,5,6,7-tetrahydroazolo[1,5-a]pyrimidines Sakhno, Yana I Murlykina, Maryna V Zbruyev, Oleksandr I Kozyryev, Anton V Shishkina, Svetlana V Sysoiev, Dmytro Musatov, Vladimir I Desenko, Sergey M Chebanov, Valentyn A Beilstein J Org Chem Full Research Paper Four-component reactions of 3-amino-1,2,4-triazole or 5-amino-1H-pyrazole-4-carbonitrile with aromatic aldehydes and pyruvic acid or its esters under ultrasonication were studied. Unusual for such a reaction type, a cascade of elementary stages led to the formation of 7-azolylaminotetrahydroazolo[1,5-a]pyrimidines. Beilstein-Institut 2020-02-27 /pmc/articles/PMC7059450/ /pubmed/32180844 http://dx.doi.org/10.3762/bjoc.16.27 Text en Copyright © 2020, Sakhno et al. https://creativecommons.org/licenses/by/4.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0). Please note that the reuse, redistribution and reproduction in particular requires that the authors and source are credited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Sakhno, Yana I
Murlykina, Maryna V
Zbruyev, Oleksandr I
Kozyryev, Anton V
Shishkina, Svetlana V
Sysoiev, Dmytro
Musatov, Vladimir I
Desenko, Sergey M
Chebanov, Valentyn A
Ultrasonic-assisted unusual four-component synthesis of 7-azolylamino-4,5,6,7-tetrahydroazolo[1,5-a]pyrimidines
title Ultrasonic-assisted unusual four-component synthesis of 7-azolylamino-4,5,6,7-tetrahydroazolo[1,5-a]pyrimidines
title_full Ultrasonic-assisted unusual four-component synthesis of 7-azolylamino-4,5,6,7-tetrahydroazolo[1,5-a]pyrimidines
title_fullStr Ultrasonic-assisted unusual four-component synthesis of 7-azolylamino-4,5,6,7-tetrahydroazolo[1,5-a]pyrimidines
title_full_unstemmed Ultrasonic-assisted unusual four-component synthesis of 7-azolylamino-4,5,6,7-tetrahydroazolo[1,5-a]pyrimidines
title_short Ultrasonic-assisted unusual four-component synthesis of 7-azolylamino-4,5,6,7-tetrahydroazolo[1,5-a]pyrimidines
title_sort ultrasonic-assisted unusual four-component synthesis of 7-azolylamino-4,5,6,7-tetrahydroazolo[1,5-a]pyrimidines
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059450/
https://www.ncbi.nlm.nih.gov/pubmed/32180844
http://dx.doi.org/10.3762/bjoc.16.27
work_keys_str_mv AT sakhnoyanai ultrasonicassistedunusualfourcomponentsynthesisof7azolylamino4567tetrahydroazolo15apyrimidines
AT murlykinamarynav ultrasonicassistedunusualfourcomponentsynthesisof7azolylamino4567tetrahydroazolo15apyrimidines
AT zbruyevoleksandri ultrasonicassistedunusualfourcomponentsynthesisof7azolylamino4567tetrahydroazolo15apyrimidines
AT kozyryevantonv ultrasonicassistedunusualfourcomponentsynthesisof7azolylamino4567tetrahydroazolo15apyrimidines
AT shishkinasvetlanav ultrasonicassistedunusualfourcomponentsynthesisof7azolylamino4567tetrahydroazolo15apyrimidines
AT sysoievdmytro ultrasonicassistedunusualfourcomponentsynthesisof7azolylamino4567tetrahydroazolo15apyrimidines
AT musatovvladimiri ultrasonicassistedunusualfourcomponentsynthesisof7azolylamino4567tetrahydroazolo15apyrimidines
AT desenkosergeym ultrasonicassistedunusualfourcomponentsynthesisof7azolylamino4567tetrahydroazolo15apyrimidines
AT chebanovvalentyna ultrasonicassistedunusualfourcomponentsynthesisof7azolylamino4567tetrahydroazolo15apyrimidines

Ejemplares similares