Autologous Platelet-Rich Gel Treatment of Chronic Nonhealing Ulcerated Tophaceous Gout

Ulcers resulting from tophaceous gout are uncommon and very difficult to heal. Here we report a case with chronic refractory tophaceous gout, not responding to conventional treatment modality for several months in a 39-year-old man with a 12-year history of gout with recurrent acute arthritis attack...

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Detalles Bibliográficos
Autores principales: Chen, Dawei, Wang, Chun, Cui, Lina, Ran, Xingwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059477/
https://www.ncbi.nlm.nih.gov/pubmed/32180603
http://dx.doi.org/10.4103/ijd.IJD_157_18
Descripción
Sumario:Ulcers resulting from tophaceous gout are uncommon and very difficult to heal. Here we report a case with chronic refractory tophaceous gout, not responding to conventional treatment modality for several months in a 39-year-old man with a 12-year history of gout with recurrent acute arthritis attacks. Two times after treatment with autologous platelet-rich gel (APG), the ulcer healed finally for 2 months. This is the first study to confirm that APG can improve tophus ulcer healing. Based on conventional medical therapy and standard debridement, APG might be a novel and effective method to stimulate tophus ulcer healing.

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