Autologous Platelet-Rich Gel Treatment of Chronic Nonhealing Ulcerated Tophaceous Gout

Ulcers resulting from tophaceous gout are uncommon and very difficult to heal. Here we report a case with chronic refractory tophaceous gout, not responding to conventional treatment modality for several months in a 39-year-old man with a 12-year history of gout with recurrent acute arthritis attack...

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Autores principales: Chen, Dawei, Wang, Chun, Cui, Lina, Ran, Xingwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059477/
https://www.ncbi.nlm.nih.gov/pubmed/32180603
http://dx.doi.org/10.4103/ijd.IJD_157_18
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author Chen, Dawei
Wang, Chun
Cui, Lina
Ran, Xingwu
author_facet Chen, Dawei
Wang, Chun
Cui, Lina
Ran, Xingwu
author_sort Chen, Dawei
collection PubMed
description Ulcers resulting from tophaceous gout are uncommon and very difficult to heal. Here we report a case with chronic refractory tophaceous gout, not responding to conventional treatment modality for several months in a 39-year-old man with a 12-year history of gout with recurrent acute arthritis attacks. Two times after treatment with autologous platelet-rich gel (APG), the ulcer healed finally for 2 months. This is the first study to confirm that APG can improve tophus ulcer healing. Based on conventional medical therapy and standard debridement, APG might be a novel and effective method to stimulate tophus ulcer healing.
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spelling pubmed-70594772020-03-16 Autologous Platelet-Rich Gel Treatment of Chronic Nonhealing Ulcerated Tophaceous Gout Chen, Dawei Wang, Chun Cui, Lina Ran, Xingwu Indian J Dermatol Case Report Ulcers resulting from tophaceous gout are uncommon and very difficult to heal. Here we report a case with chronic refractory tophaceous gout, not responding to conventional treatment modality for several months in a 39-year-old man with a 12-year history of gout with recurrent acute arthritis attacks. Two times after treatment with autologous platelet-rich gel (APG), the ulcer healed finally for 2 months. This is the first study to confirm that APG can improve tophus ulcer healing. Based on conventional medical therapy and standard debridement, APG might be a novel and effective method to stimulate tophus ulcer healing. Wolters Kluwer - Medknow 2020 /pmc/articles/PMC7059477/ /pubmed/32180603 http://dx.doi.org/10.4103/ijd.IJD_157_18 Text en Copyright: © 2020 Indian Journal of Dermatology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Chen, Dawei
Wang, Chun
Cui, Lina
Ran, Xingwu
Autologous Platelet-Rich Gel Treatment of Chronic Nonhealing Ulcerated Tophaceous Gout
title Autologous Platelet-Rich Gel Treatment of Chronic Nonhealing Ulcerated Tophaceous Gout
title_full Autologous Platelet-Rich Gel Treatment of Chronic Nonhealing Ulcerated Tophaceous Gout
title_fullStr Autologous Platelet-Rich Gel Treatment of Chronic Nonhealing Ulcerated Tophaceous Gout
title_full_unstemmed Autologous Platelet-Rich Gel Treatment of Chronic Nonhealing Ulcerated Tophaceous Gout
title_short Autologous Platelet-Rich Gel Treatment of Chronic Nonhealing Ulcerated Tophaceous Gout
title_sort autologous platelet-rich gel treatment of chronic nonhealing ulcerated tophaceous gout
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059477/
https://www.ncbi.nlm.nih.gov/pubmed/32180603
http://dx.doi.org/10.4103/ijd.IJD_157_18
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AT wangchun autologousplateletrichgeltreatmentofchronicnonhealingulceratedtophaceousgout
AT cuilina autologousplateletrichgeltreatmentofchronicnonhealingulceratedtophaceousgout
AT ranxingwu autologousplateletrichgeltreatmentofchronicnonhealingulceratedtophaceousgout

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