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Transcriptional Programming of Human Mechanosensory Neuron Subtypes from Pluripotent Stem Cells

Efficient and homogeneous in vitro generation of peripheral sensory neurons may provide a framework for novel drug screening platforms and disease models of touch and pain. We discover that, by ovesssrexpressing NGN2 and BRN3A, human pluripotent stem cells can be transcriptionally programmed to diff...

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Detalles Bibliográficos
Autores principales:	Nickolls, Alec R., Lee, Michelle M., Espinoza, David F., Szczot, Marcin, Lam, Ruby M., Wang, Qi, Beers, Jeanette, Zou, Jizhong, Nguyen, Minh Q., Solinski, Hans J., AlJanahi, Aisha A., Johnson, Kory R., Ward, Michael E., Chesler, Alexander T., Bönnemann, Carsten G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059559/ https://www.ncbi.nlm.nih.gov/pubmed/31968264 http://dx.doi.org/10.1016/j.celrep.2019.12.062

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