Cargando…

Neuroprotective effect of deferoxamine on erastin-induced ferroptosis in primary cortical neurons

The iron chelator deferoxamine has been shown to inhibit ferroptosis in spinal cord injury. However, it is unclear whether deferoxamine directly protects neurons from ferroptotic cell death. By comparing the survival rate and morphology of primary neurons and SH-SY5Y cells exposed to erastin, it was...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yan, Fan, Bao-You, Pang, Yi-Lin, Shen, Wen-Yuan, Wang, Xu, Zhao, Chen-Xi, Li, Wen-Xiang, Liu, Chang, Kong, Xiao-Hong, Ning, Guang-Zhi, Feng, Shi-Qing, Yao, Xue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer - Medknow 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059591/ https://www.ncbi.nlm.nih.gov/pubmed/31997820 http://dx.doi.org/10.4103/1673-5374.274344

Ejemplares similares

Deferoxamine promotes recovery of traumatic spinal cord injury by inhibiting ferroptosis
por: Yao, Xue, et al.
Publicado: (2019)

The Protective Role of Mitochondrial Ferritin on Erastin-Induced Ferroptosis
por: Wang, Yue-Qi, et al.
Publicado: (2016)

Biochemical mechanism of erastin-induced ferroptotic cell death in neuronal cells: Role of PDI in ferroptosis
por: Hou, Ming-Jie, et al.
Publicado: (2023)

How erastin assassinates cells by ferroptosis revealed
por: Gan, Boyi
Publicado: (2022)

The Role of Erastin in Ferroptosis and Its Prospects in Cancer Therapy
por: Zhao, Yuechen, et al.
Publicado: (2020)

Arginine Expedites Erastin-Induced Ferroptosis through Fumarate
por: Guo, Xinxin, et al.
Publicado: (2023)

Synergistic Effect of Erastin Combined with Nutlin-3 on Vestibular Schwannoma Cells as p53 Modulates Erastin-Induced Ferroptosis Response
por: He, Weiwei, et al.
Publicado: (2022)

Inhibition of autophagy rescues HT22 hippocampal neurons from erastin-induced ferroptosis
por: Hanke, Nora, et al.
Publicado: (2022)

Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC
por: Xue, Wei, et al.
Publicado: (2023)

Fascin enhances the vulnerability of breast cancer to erastin-induced ferroptosis
por: Chen, Cong, et al.
Publicado: (2022)

Cysteine Dioxygenase 1 Mediates Erastin-Induced Ferroptosis in Human Gastric Cancer Cells()
por: Hao, Shihui, et al.
Publicado: (2017)

ATF3 promotes erastin-induced ferroptosis by suppressing system Xc(–)
por: Wang, Liyuan, et al.
Publicado: (2019)

Curcumin reverses erastin-induced chondrocyte ferroptosis by upregulating Nrf2
por: Zhou, Yizhao, et al.
Publicado: (2023)

The structure of erastin-bound xCT–4F2hc complex reveals molecular mechanisms underlying erastin-induced ferroptosis
por: Yan, Renhong, et al.
Publicado: (2022)

Systematic identification of a nuclear receptor-enriched predictive signature for erastin-induced ferroptosis
por: Kwon, Ok-Seon, et al.
Publicado: (2020)

miR-28-5p inhibits carcinogenesis in colon cancer cells and is necessary for erastin-induced ferroptosis
por: Hu, Jin-Cui, et al.
Publicado: (2020)

Erastin-induced ferroptosis causes physiological and pathological changes in healthy tissues of mice
por: Zhao, Jing, et al.
Publicado: (2021)

Iron Administration Overcomes Resistance to Erastin-Mediated Ferroptosis in Ovarian Cancer Cells
por: Battaglia, Anna Martina, et al.
Publicado: (2022)

Erk1/2-Dependent HNSCC Cell Susceptibility to Erastin-Induced Ferroptosis
por: Savic, Dragana, et al.
Publicado: (2023)

Liproxstatin-1 is an effective inhibitor of oligodendrocyte ferroptosis induced by inhibition of glutathione peroxidase 4
por: Fan, Bao-You, et al.
Publicado: (2020)

Lipoxygenase‐mediated generation of lipid peroxides enhances ferroptosis induced by erastin and RSL3
por: Shintoku, Ryosuke, et al.
Publicado: (2017)

Targeted exosome‐encapsulated erastin induced ferroptosis in triple negative breast cancer cells
por: Yu, Mengyu, et al.
Publicado: (2019)

Nedd4 ubiquitylates VDAC2/3 to suppress erastin-induced ferroptosis in melanoma
por: Yang, Yongfei, et al.
Publicado: (2020)

Susceptibility to erastin‐induced ferroptosis decreases during maturation in a human oligodendrocyte cell line
por: Hoshino, Tomonori, et al.
Publicado: (2020)

Corrigendum: Deferoxamine promotes recovery of traumatic spinal cord injury by inhibiting ferroptosis
Publicado: (2019)

Deferoxamine Alleviates Osteoarthritis by Inhibiting Chondrocyte Ferroptosis and Activating the Nrf2 Pathway
por: Guo, Zhou, et al.
Publicado: (2022)

Deferoxamine attenuates visual impairment in retinal ischemia‒reperfusion via inhibiting ferroptosis
por: Wang, Xiaoxuan, et al.
Publicado: (2023)

Erastin-induced ferroptosis is a regulator for the growth and function of human pancreatic islet-like cell clusters
por: Li, Xing Yu, et al.
Publicado: (2020)

Activation of the reverse transsulfuration pathway through NRF2/CBS confers erastin-induced ferroptosis resistance
por: Liu, Nan, et al.
Publicado: (2019)

Upregulation of Nrf2 Signalling and the Inhibition of Erastin-Induced Ferroptosis by Ferulic Acid in MIN6 Cells
por: Kose, Tugba, et al.
Publicado: (2022)

Erastin induces ferroptosis in cervical cancer cells via Nrf2/HO-1 signaling pathway
por: Wei, Xiaoning, et al.
Publicado: (2023)

Heme oxygenase-1-mediated neuroprotection in subarachnoid hemorrhage via intracerebroventricular deferoxamine
por: LeBlanc, Robert H., et al.
Publicado: (2016)

Corrigendum: Deferoxamine alleviates osteoarthritis by inhibiting chondrocyte ferroptosis and activating the Nrf2 pathway
por: Guo, Zhou, et al.
Publicado: (2023)

Iron Accumulates in Huntington’s Disease Neurons: Protection by Deferoxamine
por: Chen, Jianfang, et al.
Publicado: (2013)

Mechanism of Erastin-Induced Ferroptosis in MDA-MB-231 Human Breast Cancer Cells: Evidence for a Critical Role of Protein Disulfide Isomerase
por: Wang, Hongge, et al.
Publicado: (2022)

Transferrin-based radiolabeled probe predicts the sensitivity of human renal cancer cell lines to ferroptosis inducer erastin
por: Shibata, Yuki, et al.
Publicado: (2021)

Ferroptosis inducer erastin sensitizes NSCLC cells to celastrol through activation of the ROS–mitochondrial fission–mitophagy axis
por: Liu, Ming, et al.
Publicado: (2021)

Autophagy Regulates VDAC3 Ubiquitination by FBXW7 to Promote Erastin-Induced Ferroptosis in Acute Lymphoblastic Leukemia
por: Zhu, Ting, et al.
Publicado: (2021)

Overexpression of c‐Jun inhibits erastin‐induced ferroptosis in Schwann cells and promotes repair of facial nerve function
por: Gao, Dekun, et al.
Publicado: (2022)

Targeting histone deacetylase enhances the therapeutic effect of Erastin-induced ferroptosis in EGFR-activating mutant lung adenocarcinoma
por: Zhang, Tuo, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_vqbvoa29aqhqov0k3pfqn9r1fa