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Neuroprotective actions of cerebellar and pineal allopregnanolone on Purkinje cells

The brain produces steroids de novo from cholesterol, so‐called “neurosteroids.” The Purkinje cell, a cerebellar neuron, was discovered as a major site of the biosynthesis of neurosteroids including sex steroids, such as progesterone, from cholesterol in the brain. Allopregnanolone, a progesterone m...

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Detalles Bibliográficos
Autores principales: Tsutsui, Kazuyoshi, Haraguchi, Shogo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059624/
https://www.ncbi.nlm.nih.gov/pubmed/32161904
http://dx.doi.org/10.1096/fba.2019-00055

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