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Pseudomonas Quinolone Signal molecule PQS behaves like a B Class inhibitor at the I(Q) site of mitochondrial complex I

Pseudomonas aeruginosa is a Gram‐negative bacterium of the proteobacteria class, and one of the most common causes of nosocomial infections. For example, it causes chronic pneumonia in cystic fibrosis patients. Patient sputum contains 2‐heptyl‐4‐hydroxyquinoline N‐oxide [HQNO] and Pseudomonas quorum...

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Detalles Bibliográficos
Autores principales: Rieger, Bettina, Thierbach, Sven, Ommer, Miriam, Dienhart, Finja S.V., Fetzner, Susanne, Busch, Karin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059627/
https://www.ncbi.nlm.nih.gov/pubmed/32161908
http://dx.doi.org/10.1096/fba.2019-00084

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