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Uncoupling of the Electron Transport Chain Compromises Mitochondrial Oxidative Phosphorylation and Exacerbates Stroke Outcomes

OBJECTIVE: Mitochondrial dysfunction is known to be implicated in stroke, but the complex mechanisms of stroke have led to few stroke therapies. The present study to disrupted mitochondrial oxidative phosphorylation through a known electron transport chain (ETC) uncoupler, Carbonyl cyanide-4 (triflu...

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Detalles Bibliográficos
Autores principales:	Grasmick, Kimberly A, Hu, Heng, Hone, Emily A, Farooqi, Imran, Rellick, Stephanie L, Simpkins, James W, Ren, Xuefang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059652/ https://www.ncbi.nlm.nih.gov/pubmed/32149160 http://dx.doi.org/10.4172/2314-7326.1000283

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