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P-selectin blockade ameliorates lupus nephritis in MRL/lpr mice through improving renal hypoxia and evaluation using BOLD-MRI

BACKGROUND: Lupus nephritis is one of the most common and severe complications of systemic lupus erythematosus, of which poor prognosis is indicated by aggravated renal hypoxia and tubulointerstitial fibrosis. Cell adhesion molecules play a key role in the progression of lupus nephritis tubulointers...

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Detalles Bibliográficos
Autores principales: Zhang, Liwen, Chen, Sheng, Liu, Yan, Xu, Xueqin, Zhang, Qianying, Shao, Shuxin, Wang, Weiming, Li, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059679/
https://www.ncbi.nlm.nih.gov/pubmed/32138730
http://dx.doi.org/10.1186/s12967-020-02284-1

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