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Recombinant Klotho protein enhances cholesterol efflux of THP-1 macrophage-derived foam cells via suppressing Wnt/β-catenin signaling pathway

BACKGROUND: Atherosclerosis (AS) is the basis of cardiovascular diseases, characterized by chronic inflammatory and lipid metabolism disorders. Although the anti-inflammatory effect of Klotho in AS has been clearly shown, its lipid-lowering effect is unclear. In this study, we examined the effects o...

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Detalles Bibliográficos
Autores principales:	Liu, Wei, Chen, Xiujuan, Wu, Min, Li, Lin, Liu, Jiani, Shi, Jing, Hong, Tian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059691/ https://www.ncbi.nlm.nih.gov/pubmed/32138681 http://dx.doi.org/10.1186/s12872-020-01400-9

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