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Sirtuin 1 inhibits lipopolysaccharide-induced inflammation in chronic myelogenous leukemia k562 cells through interacting with the Toll-like receptor 4-nuclear factor κ B-reactive oxygen species signaling axis

BACKGROUND: Chronic myelogenous leukemia (CML) is a clonal myeloproliferative neoplasm resulting from BCR–ABL-transformed hematopoietic stem cells. Previous research has implicated multifunctional proinflammatory cytokines in CML development. It has been reported that Sirtuin 1 (SIRT1) as well as AD...

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Detalles Bibliográficos
Autores principales:	Wang, Lei, Wang, Mingming, Dou, Hongju, Lin, Wenjie, Zou, Lifang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059700/ https://www.ncbi.nlm.nih.gov/pubmed/32165863 http://dx.doi.org/10.1186/s12935-020-1152-z

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