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Mendelian Randomization Identifies CpG Methylation Sites With Mediation Effects for Genetic Influences on BMD in Peripheral Blood Monocytes
Osteoporosis is mainly characterized by low bone mineral density (BMD) and is an increasingly serious public health concern. DNA methylation is a major epigenetic mechanism that may contribute to the variation in BMD and may mediate the effects of genetic and environmental factors of osteoporosis. I...
Autores principales: | Yu, Fangtang, Qiu, Chuan, Xu, Chao, Tian, Qing, Zhao, Lan-Juan, Wu, Li, Deng, Hong-Wen, Shen, Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059767/ https://www.ncbi.nlm.nih.gov/pubmed/32180791 http://dx.doi.org/10.3389/fgene.2020.00060 |
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