PEGylated Erythropoietin Protects against Brain Injury in the MCAO-Induced Stroke Model by Blocking NF-κB Activation

Cerebral ischemia exhibits a multiplicity of pathophysiological mechanisms. During ischemic stroke, the reactive oxygen species (ROS) concentration rises to a peak during reperfusion, possibly underlying neuronal death. Recombinant human erythropoietin (EPO) supplementation is one method of treating...

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Detalles Bibliográficos
Autores principales: Im, Jun Hyung, Yeo, In Jun, Hwang, Chul Ju, Lee, Kyung Sun, Hong, Jin Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059808/
https://www.ncbi.nlm.nih.gov/pubmed/31813204
http://dx.doi.org/10.4062/biomolther.2019.147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059808/
https://www.ncbi.nlm.nih.gov/pubmed/31813204
http://dx.doi.org/10.4062/biomolther.2019.147

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