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PEGylated Erythropoietin Protects against Brain Injury in the MCAO-Induced Stroke Model by Blocking NF-κB Activation
Cerebral ischemia exhibits a multiplicity of pathophysiological mechanisms. During ischemic stroke, the reactive oxygen species (ROS) concentration rises to a peak during reperfusion, possibly underlying neuronal death. Recombinant human erythropoietin (EPO) supplementation is one method of treating...
Autores principales: | Im, Jun Hyung, Yeo, In Jun, Hwang, Chul Ju, Lee, Kyung Sun, Hong, Jin Tae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Applied Pharmacology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059808/ https://www.ncbi.nlm.nih.gov/pubmed/31813204 http://dx.doi.org/10.4062/biomolther.2019.147 |
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