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A New Histone Deacetylase Inhibitor, MHY4381, Induces Apoptosis via Generation of Reactive Oxygen Species in Human Prostate Cancer Cells

Histone deacetylase (HDAC) inhibitors represent a novel class of anticancer agents, which can be used to inhibit cell proliferation and induce apoptosis in several types of cancer cells. In this study, we investigated the anticancer activity of MHY4381, a newly synthesized HDAC inhibitor, against hu...

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Detalles Bibliográficos
Autores principales: Richa, Sachan, Dey, Prasanta, Park, Chaeun, Yang, Jungho, Son, Ji Yeon, Park, Jae Hyeon, Lee, Su Hyun, Ahn, Mee-Young, Kim, In Su, Moon, Hyung Ryong, Kim, Hyung Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059815/
https://www.ncbi.nlm.nih.gov/pubmed/31476841
http://dx.doi.org/10.4062/biomolther.2019.074