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Exploring the role of RRM domains and conserved aromatic residues in RGG motif of eIF4G-binding translation repressor protein Sbp1
Background: RNA binding proteins play crucial role in determining if a given mRNA will be translated, stored, or degraded. Sbp1 is an RGG-motif containing protein that is implicated in affecting mRNA decapping and translation. Sbp1 represses translation by binding eIF4G1 through its RGG-motif and ac...
Autores principales: | Bhatter, Nupur, Iyyappan, Rajan, Mohanan, Gayatri, Rajyaguru, Purusharth I |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059846/ https://www.ncbi.nlm.nih.gov/pubmed/32175478 http://dx.doi.org/10.12688/wellcomeopenres.14709.3 |
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