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Mechanism of sphingosine 1-phosphate clearance from blood

The interplay of sphingosine 1-phosphate (S1P) synthetic and degradative enzymes as well as S1P exporters creates concentration gradients that are a fundamental to S1P biology. Extracellular S1P levels, such as in blood and lymph, are high relative to cellular S1P. The blood-tissue S1P gradient main...

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Detalles Bibliográficos
Autores principales: Kharel, Yugesh, Huang, Tao, Salamon, Anita, Harris, Thurl E., Santos, Webster L., Lynch, Kevin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059866/
https://www.ncbi.nlm.nih.gov/pubmed/32065229
http://dx.doi.org/10.1042/BCJ20190730